Anti-CTCF Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-CTCF Polyclonal Antibody
中文名称： CCCTC结合因子(锌指蛋白)抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Mouse ; Rat
应用： ChIP ; IP ; IF ; WB
稀释比例： WB 1:500-1000. IF 1:50-200. IP 0.5μg-4μg. ChIP 5μg.

抗体信息

靶标： CTCF
别名： 11 zinc finger protein, 11 zinc finger transcriptional repressor, CCCTC binding factor (zinc finger protein), CCCTC binding factor, CTCFL paralog, Transcriptional repressor CTCF, CTCF_HUMAN
背景说明： This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Swiss Prot： P49711
Gene ID： 10664
亚细胞定位： Chromosome Nucleus centromere nucleoplasm
免疫原： Recombinant protein of human CTCF
Public Immunogen Range： 1-260aa
理论分子量： 83kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。