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Anti-PYCARD Polyclonal Antibody,BR
Anti-PYCARD Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-PYCARD Polyclonal Antibody中文名称: 包含PYD和CARD结构域蛋白抗体
规格: 100ul ; 50ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Rat ; Mouse ; Human
应用: IF ; IHC ; WB
稀释比例: WB 1:500-1000. IHC 1:50-200. IF 1:50-200.
抗体信息
靶标: PYCARD别名: TMS1, Apoptosis associated speck like protein containing a CARD, Apoptosis-associated speck-like protein containing a CARD, ASC_HUMAN, CARD 5, CARD5, Caspase recruitment domain containing protein 5, Caspase recruitment domain protein 5, Caspase recruitment domain-containing protein 5, hASC, MGC10332, PYCARD, TMS-1, PYD and CARD domain containing, PYD and CARD domain containing protein, PYD and CARD domain-containing protein, Target of methylation induced silencing 1, Target of methylation-induced silencing 1, TMS 1
背景说明: This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene.
Swiss Prot: Q9ULZ3
Gene ID: 29108
亚细胞定位: Cytoplasm Endoplasmic reticulum Mitochondrion Nucleus
免疫原: A synthetic peptide of human PYCARD
Public Immunogen Range: 1-100aa
理论分子量: 22kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。