Anti-CDH1 Polyclonal Antibody,BR

英文名称:Anti-CDH1 Polyclonal Antibody
宿主:Rabbit
别名:CADH1;Cadherin-1;CDHE;UVO;ECAD;Arc-1;CD324;LCAM

交叉反应:Human Mouse Rat
应用:WB
稀释比例:WB 1:500-1000.
蛋白分子量:97kDa
Gene ID:999
保存:Store at -20°C. Avoid freeze / thaw cycles.
储存液:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法:Affinity purification
亚型:IgG
免疫原:A synthetic peptide of human CDH1
性状:液体
亚细胞定位:Cell junction Cell membrane Endosome Golgi apparatus Single-pass type I membrane protein trans-Golgi network
Swiss Prot:P12830
背景资料:

This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16.
Public Immunogen Range:A synthetic peptide of human CDH1
克隆类型:Polyclonal Antibody
规格:50ul, 100ul,

注意：
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