Anti-CDC42 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-CDC42 Polyclonal Antibody
中文名称： 细胞分裂周期蛋白42抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Mouse ; Human
应用： IF ; IHC ; WB
稀释比例： WB 1:500-1000. IHC 1:50-200. IF 1:50-200.

抗体信息

靶标： CDC42
别名： CDC 42, CDC42Hs, Cell division control protein 42 homolog, Cell division cycle 42, Cell division cycle 42 isoform 1, Cell division cycle 42 isoform 2, dJ224A6.1.1, dJ224A6.1.2, G25K, G25K GTP binding protein, Growth regulating protein, GTP binding protein 25kD, Small GTP binding protein CDC42, CDC42_HUMAN
背景说明： The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20.
Swiss Prot： P60953
Gene ID： 998
亚细胞定位： Cell membrane Cytoplasm Cytoplasmic side Lipid-anchor Midbody centrosome cytoskeleton microtubule organizing center spindle
免疫原： Recombinant protein of human CDC42
Public Immunogen Range： 118-191aa
理论分子量： 21kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

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3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。