Anti-BAX Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-BAX Polyclonal Antibody
中文名称： Bcl2关联X蛋白抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Human ; Mouse
应用： IF ; IHC ; WB
稀释比例： WB 1:500-1000. IHC 1:50-200. IF 1:50-200.

抗体信息

靶标： BAX
别名： BCL2L4;Bax-protein;BAX_HUMAN;BAXA
背景说明： The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.
Swiss Prot： Q07812
Gene ID： 581
亚细胞定位： Cytoplasm Cytoplasm Mitochondrion membrane Single-pass membrane protein
免疫原： A synthetic peptide of human BAX
Public Immunogen Range： 1-100aa
理论分子量： 21kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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