Anti-ALDH2 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-ALDH2 Polyclonal Antibody
中文名称： 乙醛脱氢酶2抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Mouse ; Human
应用： IF ; IHC ; WB
稀释比例： WB 1:500-1000. IHC 1:50-200. IF 1:50-200.

抗体信息

靶标： ALDH2
别名： Acetaldehyde dehydrogenase 2, Aldehyde dehydrogenase 2 family (mitochondrial), Aldehyde dehydrogenase 2 family, Aldehyde dehydrogenase mitochondrial, Aldehyde dehydrogenase, mitochondrial, ALDH 2, ALDH class 2, ALDH E2, ALDH-E2, ALDH2_HUMAN, ALDHI, ALDM, Liver mitochondrial ALDH, MGC1806, Mitochondrial aldehyde dehydrogenase 2, MS767, Nucleus encoded mitochondrial aldehyde dehydrogenase 2
背景说明： This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of East Asians have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among East Asians than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Swiss Prot： P05091
Gene ID： 217
亚细胞定位： Mitochondrion matrix
免疫原： Recombinant protein of human ALDH2
Public Immunogen Range： 321-480aa
理论分子量： 56kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。