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- Anti-SMAD7 Polyclonal Antibody,BR
Anti-SMAD7 Polyclonal Antibody,BR
Anti-SMAD7 Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-SMAD7 Polyclonal Antibody中文名称: Smad7抗体
规格: 100ul ; 50ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Rat ; Human ; Mouse
应用: IF ; WB
稀释比例: WB 1:500-1000. IF 1:50-200.
抗体信息
靶标: SMAD7别名: CRCS3;MADH7;MADH8;Hsmad7;MAD homolog 8
背景说明: The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene.
Swiss Prot: O15105
Gene ID: 4092
亚细胞定位: Cytoplasm Nucleus
免疫原: A synthetic peptide of human SMAD7
Public Immunogen Range: 220-420aa
理论分子量: 46kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。