Anti-WISP2 Polyclonal Antibody,BR

英文名称:Anti-WISP2 Polyclonal Antibody
宿主:Rabbit
别名:CCN5;CT58;CTGF-L
交叉反应:Human Mouse Rat
应用:WB IHC
稀释比例:WB 1:500-2000. IHC 1:50-200.
蛋白分子量:27/23kDa
Gene ID:8839
保存:Store at -20°C. Avoid freeze / thaw cycles.
储存液:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法:Affinity purification
亚型:IgG
免疫原:Recombinant protein of human WISP2
性状:液体
亚细胞定位:Secreted
Swiss Prot:O76076
背景资料:

This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain. The encoded protein lacks the CT domain which is implicated in dimerization and heparin binding. It is 72% identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover.
Public Immunogen Range:Recombinant protein of human WISP2
克隆类型:Polyclonal Antibody
规格:50ul, 100ul,

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