Anti-BCL2L11 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-BCL2L11 Polyclonal Antibody
中文名称： 细胞死亡调解子抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human
应用： IHC
稀释比例： IHC 1:50-100

抗体信息

靶标： BCL2L11
别名： Bcl-2 interacting mediator of cell death, Bcl-2-like protein 11, Bcl2-L-11, Bcl2-interacting mediator of cell death, BCL2L11, BAM, BIM-alpha6, BIM-beta6, BIM-beta7, BimEL, BimL, BOD, B2L11_HUMAN,BIM
背景说明： The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified.
Swiss Prot： O43521
Gene ID： 10018
亚细胞定位： Endomembrane system Mitochondrion Peripheral membrane protein
免疫原： Recombinant protein of human BCL2L11
Public Immunogen Range： 30-130aa
理论分子量： 22/13/19/9/4kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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