Anti-ZBTB33 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-ZBTB33 Polyclonal Antibody
中文名称： 锌指蛋白348抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Human
应用： WB ; IHC
稀释比例： WB 1:1000-3000. IHC 1:100-500

抗体信息

靶标： ZBTB33
别名： Kaiso, Kaiso protein, Kaiso transcription factor, KAISO_HUMAN, Transcriptional regulator Kaiso, ZBTB 33, ZBTB33, Zinc finger and BTB domain containing 33, Zinc finger and BTB domain containing 33, Zinc finger and BTB domain-containing protein 33, Zinc finger transcription factor Kaiso, ZNF 348, ZNF Kaiso, ZNF348
背景说明： This gene encodes a transcriptional regulator with bimodal DNA-binding specificity, which binds to methylated CGCG and also to the non-methylated consensus KAISO-binding site TCCTGCNA. The protein contains an N-terminal POZ/BTB domain and 3 C-terminal zinc finger motifs. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. It may contribute to the repression of target genes of the Wnt signaling pathway, and may also activate transcription of a subset of target genes by the recruitment of catenin delta-2 (CTNND2). Its interaction with catenin delta-1 (CTNND1) inhibits binding to both methylated and non-methylated DNA. It also interacts directly with the nuclear import receptor Importin-α2 (also known as karyopherin alpha2 or RAG cohort 1), which may mediate nuclear import of this protein. Alternatively spliced transcript variants encoding the same protein have been identified.
Swiss Prot： Q86T24
Gene ID： 10009
亚细胞定位： Cytoplasm Nucleus
免疫原： Recombinant protein of human ZBTB33
Public Immunogen Range： 523-672aa
理论分子量： 74kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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