Anti-COMT Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-COMT Polyclonal Antibody
中文名称： 邻苯二酚-O-甲基转移酶抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Human
应用： IP ; WB
稀释比例： WB 1:500-2000. IP 0.5μg-4μg.

抗体信息

靶标： COMT
别名： Catechol O methyltransferase, Catechol O-methyltransferase, COMT, COMT_HUMAN, EC 2.1.1.6
背景说明： Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.
Swiss Prot： P21964
Gene ID： 1312
亚细胞定位： Cell membrane Cytoplasm Extracellular side Single-pass type II membrane protein
免疫原： Recombinant protein of human COMT
Public Immunogen Range： 42-221aa
理论分子量： 30kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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