Anti-APOB Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-APOB Polyclonal Antibody
中文名称： 载脂蛋白B抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Rat ; Human
应用： IF ; WB
稀释比例： WB 1:500-1000. IF 1:50-200.

抗体信息

靶标： APOB
别名： FLDB;LDLCQ4;apoB-100;apoB-48
背景说明： This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels.
Swiss Prot： P04114
Gene ID： 338
亚细胞定位： Cytoplasm Secreted
免疫原： Recombinant protein of human APOB
Public Immunogen Range： 28-330aa
理论分子量： 516kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。