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- Anti-F8 Polyclonal Antibody,BR
Anti-F8 Polyclonal Antibody,BR
Anti-F8 Polyclonal Antibody
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英文名称:Anti-F8 Polyclonal Antibody
宿主:Rabbit
别名:AHF;DXS1253E;F8B;F8C;FVIII;HEMA
交叉反应:Mouse Rat
应用:WB
稀释比例:WB 1:500-2000.
蛋白分子量:267kDa
Gene ID:2157
保存:Store at -20°C. Avoid freeze / thaw cycles.
储存液:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法:Affinity purification
亚型:IgG
免疫原:Recombinant protein of human F8
性状:液体
亚细胞定位:Secreted extracellular space
Swiss Prot:P00451
背景资料:
This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.
Public Immunogen Range:Recombinant protein of human F8
克隆类型:Polyclonal Antibody
规格:50ul, 100ul,
注意:
1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2. 为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。