Anti-GNB3 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-GNB3 Polyclonal Antibody
中文名称： 鸟嘌呤核苷酸结合蛋白(G蛋白)亚基β3抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Rat ; Human
应用： IF ; WB
稀释比例： WB 1:500-1000. IF 1:50-200.

抗体信息

靶标： GNB3
别名： G protein beta 3, Gnb3, Guanine nucleotide binding protein (G protein), beta polypeptide 3, Guanine nucleotide binding protein G, Hypertension associated protein, IG, SG, Transducin beta chain 3, Tsubunit beta 3, GBB3_HUMAN
背景说明： Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit which belongs to the WD repeat G protein beta family. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
Swiss Prot： P16520
Gene ID： 2784
亚细胞定位： Cytosol secreted Plasma Membrane
免疫原： Recombinant protein of human GNB3
Public Immunogen Range： 1-340aa
理论分子量： 37kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
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注意事项 Considerations

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