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- Anti-LRP1 Polyclonal Antibody,BR
Anti-LRP1 Polyclonal Antibody,BR
Anti-LRP1 Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-LRP1 Polyclonal Antibody中文名称: 低密度脂蛋白受体相关蛋白1抗体
规格: 50ul ; 100ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Human ; Mouse ; Rat
应用: IHC ; WB
稀释比例: WB 1:500-1000.IHC 1:50-100
抗体信息
靶标: LRP1别名: A2MR;APOER;APR;CD91;IGFBP3R;KPA;LRP;LRP1A;TGFBR5;LDL receptor related protein 1
背景说明: This gene encodes a member of the low-density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712). This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2-macroglobulin-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer's disease patients.
Swiss Prot: Q07954
Gene ID: 4035
亚细胞定位: Cell membrane Cytoplasm Extracellular side Membrane Nucleus Peripheral membrane protein Single-pass type I membrane protein coated pit
免疫原: Recombinant protein of human LRP1
Public Immunogen Range: 4401-4500aa
理论分子量: 32/504kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 0.03% Proclin300,50% glycerol,pH7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。