Anti-PRKAR2A Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-PRKAR2A Polyclonal Antibody
中文名称： cAMP依赖蛋白激酶调控亚基Iiα抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Human ; Mouse
应用： IF ; WB
稀释比例： WB 1:1000-2000.IF 1:50-200

抗体信息

靶标： PRKAR2A
别名： PKR2,PRKAR2,cAMP-dependent protein kinase type II-alpha regulatory subunit
背景说明： cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase. This subunit has been shown to regulate protein transport from endosomes to the Golgi apparatus and further to the endoplasmic reticulum (ER).
Swiss Prot： P13861
Gene ID： 5576
亚细胞定位： Cell membrane Cytoplasm
免疫原： Recombinant protein of human PRKAR2A
Public Immunogen Range： 1-404aa
理论分子量： 46kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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