Anti-CDK6 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-CDK6 Polyclonal Antibody
中文名称： 周期素依赖性激酶6抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Human
应用： IHC ; IF ; IP ; WB
稀释比例： WB 1:500-1000. IHC 1:50-200. IF 1:50-200. IP 0.5μg-4μg.

抗体信息

靶标： CDK6
别名： MCPH12;PLSTIRE;CDKN6;Cyclin-dependent kinase 6;Cell division protein kinase 6
背景说明： The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Expression of this gene is up-regulated in some types of cancer. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Swiss Prot： Q00534
Gene ID： 1021
亚细胞定位： Cell projection Cytoplasm Nucleus centrosome cytoskeleton microtubule organizing center ruffle
免疫原： Recombinant protein of human CDK6
Public Immunogen Range： 226-326aa
理论分子量： 37kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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