Anti-KPNA2 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-KPNA2 Polyclonal Antibody
中文名称： 核蛋白相互作用蛋白2抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Human
应用： IP ; WB
稀释比例： WB 1:500-2000. IP 0.5μg-4μg.

抗体信息

靶标： KPNA2
别名： IPOA1;QIP2;RCH1;SRP1-alpha;SRP1alpha
背景说明： The import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy-independent docking of the protein to the nuclear envelope and the second is an energy-dependent translocation through the nuclear pore complex. Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. Proteins involved in the first step of nuclear import have been identified in different systems. These include the Xenopus protein importin and its yeast homolog, SRP1 (a suppressor of certain temperature-sensitive mutations of RNA polymerase I in Saccharomyces cerevisiae), which bind to the NLS. KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination. Alternative splicing results in multiple transcript variants.
Swiss Prot： P52292
Gene ID： 3838
亚细胞定位： Cytoplasm Nucleus
免疫原： Recombinant protein of human KPNA2
Public Immunogen Range： 1-290aa
理论分子量： 58kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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