Anti-CYBB Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-CYBB Polyclonal Antibody
中文名称： NADPH氧化酶2抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Mouse ; Rat
应用： IF ; IHC ; WB
稀释比例： WB 1:500-1000. IHC 1:50-200. IF 1:50-200.

抗体信息

靶标： CYBB
别名： NOX2,AMCBX2,CGD,CGD91-phox,CY24B_HUMAN,CYBB,Cytochrome b 245, beta polypeptide,Cytochrome b(558) beta chain,Cytochrome b(558) subunit beta,Cytochrome b-245 heavy chain
背景说明： Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.
Swiss Prot： P04839
Gene ID： 1536
亚细胞定位： Cell membrane Multi-pass membrane protein
免疫原： A synthetic peptide of human CYBB
Public Immunogen Range： 100-200aa
理论分子量： 65kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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