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- Anti-EWSR1 Polyclonal Antibody,BR
Anti-EWSR1 Polyclonal Antibody,BR
Anti-EWSR1 Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-EWSR1 Polyclonal Antibody中文名称: RNA结合蛋白EWS抗体
规格: 100ul ; 50ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Human
应用: WB
稀释比例: WB 1:500-2000
抗体信息
靶标: EWSR1别名: bK984G1.4, bK984G1.4 Ewing sarcoma breakpoint region 1 protein, Ewing sarcoma breakpoint region 1, Ewing sarcoma breakpoint region 1 protein, Ewings sarcoma EWS Fli1 type 1 oncogene, EWS, EWS oncogene, EWS_HUMAN, EWSR 1, Ewsr1, EWSR1 protein, RNA binding protein EWS, RNA-binding protein EWS
背景说明: This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a t(11;22)(q24;q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14.
Swiss Prot: Q01844
Gene ID: 2130
亚细胞定位: Cell membrane Cytoplasm Nucleus
免疫原: Recombinant protein of human EWSR1
Public Immunogen Range: 100-300aa
理论分子量: 68kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。