Anti-CFB Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-CFB Polyclonal Antibody
中文名称： 补体因子B抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Human ; Mouse
应用： IF ; IHC ; WB
稀释比例： WB 1:500-1000. IHC 1:50-200. IF 1:50-200.

抗体信息

靶标： CFB
别名： AHUS4, B factor properdin, Factor B , BF, BFD, C3 proaccelerator, C3 proactivator, C3/C5 convertase, CFAB, CFAB_HUMAN, CFB, Complement Factor B, Complement factor B Bb fragment, FB, FBI12, GBG, Glycine rich beta glycoprotein, Glycine-rich beta glycoprotein, H2 Bf, H2BF, PBF2, Properdin factor B
背景说明： This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2.
Swiss Prot： P00751
Gene ID： 629
亚细胞定位： Secreted
免疫原： Recombinant protein of human CFB
Public Immunogen Range： 26-259aa
理论分子量： 68/85kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.03% Proclin300，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。