Anti-LIG4 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-LIG4 Polyclonal Antibody
中文名称： DNA连接酶4抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Mouse ; Human
应用： IHC ; WB
稀释比例： WB 1:500-1000. IHC 1:50-200.

抗体信息

靶标： LIG4
别名： LIG4, DNA ligase IV ATP dependent, DNA ligase IV ATP dependent, DNA joinase, DNA joinase, DNA ligase 4, DNA ligase IV, DNA repair enzyme, DNA repair enzyme, DNLI4_HUMAN, LIG 4, LIG4, LIG-4, Ligase IV, Ligase IV, Ligase IV DNA ATP dependent, Polydeoxyribonucleotide synthase [ATP] 4, Polydeoxyribonucleotide synthase 4, Polydeoxyribonucleotide synthase, Polydeoxyribonucleotide synthase, Polynucleotide ligase, Polynucleotide ligase, Sealase
背景说明： The protein encoded by this gene is a DNA ligase that joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. This protein is essential for V(D)J recombination and DNA double-strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X-ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA-dependent protein kinase (DNA-PK). Both XRCC4 and DNA-PK are known to be required for NHEJ. The crystal structure of the complex formed by this protein and XRCC4 has been resolved. Defects in this gene are the cause of LIG4 syndrome. Alternatively spliced transcript variants encoding the same protein have been observed.
Swiss Prot： P49917
Gene ID： 3981
亚细胞定位： Nucleus
免疫原： Recombinant protein of human LIG4
Public Immunogen Range： 1-210aa
理论分子量： 104kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.03% Proclin300，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
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注意事项 Considerations

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