Anti-CCND2 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-CCND2 Polyclonal Antibody
中文名称： 细胞周期蛋白D2抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Rat ; Mouse
应用： WB
稀释比例： WB 1:500-1000.

抗体信息

靶标： CCND2
别名： CCND 2, CCND2, CyclinD2, G1/S specific cyclin D2, KIAK0002, MGC102758, CCND2_HUMAN, G1/S-specific cyclin-D2
背景说明： The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK4 or CDK6 and functions as a regulatory subunit of the complex, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors. Mutations in this gene are associated with megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 3 (MPPH3).
Swiss Prot： P30279
Gene ID： 894
亚细胞定位： Cytoplasm Membrane Nucleus
免疫原： Recombinant Protein of human CCND2
Public Immunogen Range： 1-289aa
理论分子量： 24/33kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
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注意事项 Considerations

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3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。