Anti-BIN1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-BIN1 Polyclonal Antibody
中文名称： Myc 盒依赖性相互作用蛋白 1抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Rat
应用： IF ; IHC ; WB
稀释比例： WB 1:500-1000. IHC 1:50-200. IF 1:20-50.

抗体信息

靶标： BIN1
别名： Amphiphysin like protein, AMPH 2, AMPH2, Amphiphysin 2, Amphiphysin II, Amphiphysin like protein, amphiphysin-like, AMPHL, Box Dependant MYC Interacting Protein 1, Bridging Integrator 1, DKFZp547F068, MGC10367, MGC105358, Myc box dependent interacting protein 1, SH3P9, BIN1_HUMAN
背景说明： This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in several transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.
Swiss Prot： O00499
Gene ID： 274
亚细胞定位： Cytoplasm Nucleus
免疫原： Recombinant protein of human BIN1
Public Immunogen Range： 230-409aa
理论分子量： 65kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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