Anti-DDB2 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-DDB2 Polyclonal Antibody
中文名称： 损伤特异性DNA结合蛋白2抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Human ; Mouse
应用： IF ; WB
稀释比例： WB 1:500-2000. IF 1:50-200.

抗体信息

靶标： DDB2
别名： damage-specific DNA binding protein 2, Damage-specific DNA-binding protein 2, DDB p48 subunit, Ddb2, DDB2_HUMAN, DDBb, DNA damage-binding protein 2, UV-damaged DNA-binding protein 2, UV-DDB 2
背景说明： This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene.
Swiss Prot： Q92466
Gene ID： 1643
亚细胞定位： Nucleus
免疫原： Recombinant protein of human DDB2
Public Immunogen Range： 1-315aa
理论分子量： 48kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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