Anti-UBE2D1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-UBE2D1 Polyclonal Antibody
中文名称： 泛素结合酶E2D1抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Mouse ; Human
应用： IHC ; WB
稀释比例： WB 1:500-2000. IHC 1:50-200.

抗体信息

靶标： UBE2D1
别名： E2(17)KB1;SFT;UBC4/5;UBCH5;UBCH5A
背景说明： The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Two transcript variants encoding different isoforms have been found for this gene.
Swiss Prot： P51668
Gene ID： 7321
亚细胞定位： Cytoplasm
免疫原： Recombinant protein of human UBE2D1
Public Immunogen Range： 1-147aa
理论分子量： 17kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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