Anti-MCM6 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-MCM6 Polyclonal Antibody
中文名称： 微小染色体维持蛋白6抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Rat ; Human
应用： IP ; IF ; WB
稀释比例： WB 1:500-2000. IF 1:50-200. IP 0.5μg-4μg.

抗体信息

靶标： MCM6
别名： DNA replication licensing factor MCM6, MCG40308, Mcm6, MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe), MCM6 minichromosome maintenance deficient 6, MCM6_HUMAN, Minichromosome maintenance complex component 6, Minichromosome maintenance deficient (mis5 S. pombe) 6, Minichromosome maintenance deficient 6 homolog, Minichromosome maintenance protein 6, Mis5, MIS5 homolog, P105MCM
背景说明： The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication. Single nucleotide polymorphisms in the intron regions of this gene are associated with differential transcriptional activation of the promoter of the neighboring lactase gene and, thereby, influence lactose intolerance in early adulthood.
Swiss Prot： Q14566
Gene ID： 4175
亚细胞定位： Nucleus
免疫原： Recombinant protein of human MCM6
Public Immunogen Range： 562-821aa
理论分子量： 93kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
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注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。