Anti-PSMC2 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-PSMC2 Polyclonal Antibody
中文名称： PSMC2抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Mouse ; Rat
应用： WB
稀释比例： WB 1:500-2000

抗体信息

靶标： PSMC2
别名： 26S protease regulatory subunit 7, PRS7_HUMAN, 26S protease complex, 26S proteasome AAA-ATPase subunit RPT1, mammalian suppressor of sgv-1 of yeast, MSS1, Nbla10058, protease 26S subunit 7, proteasome 26S ATPase subunit 2, Proteasome 26S subunit ATPase 2, proteasome 26S subunit ATPase 2, Protein MSS1, putative protein product of Nbla10058, S7 antibody
背景说明： The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit has been shown to interact with several of the basal transcription factors so, in addition to participation in proteasome functions, this subunit may participate in the regulation of transcription. This subunit may also compete with PSMC3 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Swiss Prot： P35998
Gene ID： 5701
亚细胞定位： Cytoplasm Nucleus P-body
免疫原： Recombinant protein of human PSMC2
Public Immunogen Range： 1-160aa
理论分子量： 49kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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