Anti-BMPR1B Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-BMPR1B Polyclonal Antibody
中文名称： 骨形态发生蛋白受体IB型抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Mouse ; Human
应用： IF ; IHC ; WB
稀释比例： WB 1:500-1000. IHC 1:100-500. IF 1:50-200.

抗体信息

靶标： BMPR1B
别名： ALK-6;ALK6;AMDD;BDA1D;BDA2;CDw293
背景说明： This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene.
Swiss Prot： O00238
Gene ID： 658
亚细胞定位： Membrane Single-pass type I membrane protein
免疫原： Recombinant protein of human BMPR1B
Public Immunogen Range： 1-126aa
理论分子量： 57kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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