Anti-E2F1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-E2F1 Polyclonal Antibody
中文名称： E2F细胞周期相关转录因子1抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Rat ; Human
应用： IF ; WB
稀释比例： WB 1:500-1000.IF 1:20-100

抗体信息

靶标： E2F1
别名： E2F-1;RBAP1;RBBP3;RBP3
背景说明： The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis.
Swiss Prot： Q01094
Gene ID： 1869
亚细胞定位： Nucleus
免疫原： Recombinant protein of human E2F1
Public Immunogen Range： 200-301aa
理论分子量： 47kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.03% Proclin300，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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