Anti-NR3C1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-NR3C1 Polyclonal Antibody
中文名称： 核受体亚家族3,C组成员1抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Human ; Mouse
应用： IF ; IHC ; WB
稀释比例： WB 1:500-2000.IHC 1:50-200.IF 1:50-200

抗体信息

靶标： NR3C1
别名： GCCR;GCR;GCRST;GR;GRL;glucocorticoid receptor
背景说明： This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175).
Swiss Prot： P04150
Gene ID： 2908
亚细胞定位： Cytoplasm Mitochondrion Nucleus Nucleus
免疫原： Recombinant protein of human NR3C1
Public Immunogen Range： 1-280aa
理论分子量： 52/76/61/65/82/86kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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