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Anti-VDR Polyclonal Antibody,BR
Anti-VDR Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-VDR Polyclonal Antibody中文名称: 维生素D(1,25-二羟基维生素D3)受体抗体
规格: 100ul ; 50ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Human ; Mouse
应用: IF ; WB
稀释比例: WB 1:500-1000. IF 1:50-200.
抗体信息
靶标: VDR别名: Vitamin D3 receptor, 125 dihydroxyvitamin D3 receptor, 1 antibody 1,25-@dihydroxyvitamin D3 receptor, 125 dihydroxyvitamin D3 receptor, 25-dihydroxyvitamin D3 receptor, NR1I1, Nuclear receptor subfamily 1 group I member 1, VDR, VDR_HUMAN, Vitamin D (1,25- dihydroxyvitamin D3) receptor, Vitamin D hormone receptor, Vitamin D receptor, Vitamin D3 receptor
背景说明: This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins.
Swiss Prot: P11473
Gene ID: 7421
亚细胞定位: Nucleus
免疫原: A synthetic peptide of human VDR
Public Immunogen Range: 1-100aa
理论分子量: 48kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。