Anti-PDCD6IP Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-PDCD6IP Polyclonal Antibody
中文名称： 调亡诱导因子6相互作用蛋白/多巴胺受体相互作用蛋白4抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Rat ; Mouse
应用： IF ; WB
稀释比例： WB 1:200-2000.IF 1:50-200

抗体信息

靶标： PDCD6IP
别名： AIP1, ALG 2 interacting protein 1, ALG-2-interacting protein 1, ALG2 interacting protein X, Alix, Apoptosis linked gene 2 interacting protein X, Dopamine receptor interacting protein 4, DRIP4, HP95, KIAA1375, MGC17003, PDC6I_HUMAN, PDCD6 interacting protein, PDCD6-interacting protein, PDCD6IP, Programmed cell death 6 interacting protein, Programmed cell death 6-interacting protein
背景说明： This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15.
Swiss Prot： Q8WUM4
Gene ID： 10015
亚细胞定位： Cytoplasm Melanosome centrosome cytoskeleton cytosol microtubule organizing center
免疫原： Recombinant protein of human PDCD6IP
Public Immunogen Range： 1-180aa
理论分子量： 96kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
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注意事项 Considerations

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3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。