Anti-DNMT3L Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-DNMT3L Polyclonal Antibody
中文名称： DNA甲基转移酶3L抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Human ; Mouse
应用： IHC ; WB
稀释比例： WB 1:500-2000.IHC 1:50-200

抗体信息

靶标： DNMT3L
别名： Cytosine 5 methyltransferase 3 like protein, DNA (cytosine 5 ) methyltransferase 3 like, DNA (cytosine-5)-methyltransferase 3-like, DNA Cytosine 5 Methyltransferase 3 Like Protein, DNA Methyltransferase 3 Like Protein, DNM3L_HUMAN, Dnmt 3L, Dnmt3l, Human cytosine 5 methyltransferase 3 like protein, MGC1090
背景说明： CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases, but is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, it does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Swiss Prot： Q9UJW3
Gene ID： 29947
亚细胞定位： Nucleus
免疫原： A synthetic peptide of human DNMT3L
Public Immunogen Range： 100-200aa
理论分子量： 43kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.03% Proclin300，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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