Anti-CYP3A4 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-CYP3A4 Polyclonal Antibody
中文名称： 细胞色素P450 3A4抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Mouse ; Rat
应用： IHC ; WB ; IF
稀释比例： WB 1:500-1000. IHC 1:20-50. IF 1:50-100.

抗体信息

靶标： CYP3A4
别名： CP33;CP34;CYP3A;CYP3A3;CYPIIIA3;CYPIIIA4;HLP;NF-25;P450C3;P450PCN1
背景说明： This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified.
Swiss Prot： P08684
Gene ID： 1576
亚细胞定位： Cytoplasm Cell membrane
免疫原： Recombinant protein of human CYP3A4
Public Immunogen Range： 244-503aa
理论分子量： 57kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.03% Proclin300，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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