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Anti-LEPR Polyclonal Antibody,BR
Anti-LEPR Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-LEPR Polyclonal Antibody中文名称: 瘦素受体抗体
规格: 100ul ; 50ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Human ; Rat
应用: WB ; IF
稀释比例: WB 1:500-1000. IF 1:50-200
抗体信息
靶标: LEPR别名: obl, CD 295, CD295, CD295 antigen, Db, Fa, HuB219, LEP R, LEPR, LEPROT, Leptin receptor fatty, Leptin receptor gene related protein, Leptin receptor precursor, OB R, OB-R, OB R gene related protein, OB receptor, OB-RGRP, Obr, Ob-R a/b/c/d/e, LEPR_HUMAN, LEPRD, Leptin receptor
背景说明: The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).
Swiss Prot: P48357
Gene ID: 3953
亚细胞定位: Cell membrane Secreted Single-pass type I membrane protein
免疫原: Recombinant protein of human LEPR
Public Immunogen Range: 1070-1165aa
理论分子量: 132kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。
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