Anti-PSME2 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-PSME2 Polyclonal Antibody
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Human
应用： WB
稀释比例： WB 1:500-1000.

抗体信息

别名： PA28B;PA28beta;REGbeta
背景说明： The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the beta subunit of the 11S regulator, one of the two 11S subunits that is induced by gamma-interferon. Three beta and three alpha subunits combine to form a heterohexameric ring. Six pseudogenes have been identified on chromosomes 4, 5, 8, 10 and 13.
Swiss Prot： Q9UL46
Gene ID： 5721
亚细胞定位： Cytosol Nucleus secreted
免疫原： Recombinant protein of human PSME2
Public Immunogen Range： 1-239aa
理论分子量： 27kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide,50% glycerol,pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.外观(性状) 液体

产品介绍 Product Introduction

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注意事项 Considerations

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