Anti-MLKL Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-MLKL Polyclonal Antibody
中文名称： 混合系列蛋白激酶样结构域抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Human
应用： IF ; IHC ; WB
稀释比例： WB 1:500-2000. IHC 1:50-200. IF 1:50-200.

抗体信息

靶标： MLKL
别名： 9130019I15Rik, FLJ34389, hMLKL, Mixed lineage kinase domain like, Mixed lineage kinase domain like protein, Mixed lineage kinase domain like pseudokinase, Mixed lineage kinase domain-like protein, Mlkl, MLKL_HUMAN
背景说明： This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to lack protein kinase activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (Rip3), which is a key signaling molecule in necroptosis pathway. Knockout of this gene in mice showed that it is essential for necroptosis. Alternatively spliced transcript variants have been found for this gene.
Swiss Prot： Q9D2Y4
Gene ID： 74568
亚细胞定位： Plasma membrane
免疫原： Recombinant protein of mouse MLKL
Public Immunogen Range： 1-53aa
理论分子量： 54kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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