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Anti-ACY1 Polyclonal Antibody,BR
Anti-ACY1 Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-ACY1 Polyclonal Antibody中文名称: 氨基酰化酶1抗体
规格: 100ul ; 50ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Rat ; Mouse ; Human
应用: IF ; WB
稀释比例: WB 1:500-2000. IF 1:10-100.
抗体信息
靶标: ACY1别名: ACY-1;ACY1D;HEL-S-5
背景说明: This gene encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene, as represented in GeneID:100526760. A related pseudogene has been identified on chromosome 18.
Swiss Prot: Q03154
Gene ID: 95
亚细胞定位: Cytoplasm Nucleus
免疫原: Recombinant protein of human ACY1
Public Immunogen Range: 1-408aa
理论分子量: 46kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。
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