Anti-ASPH Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-ASPH Polyclonal Antibody
中文名称： 天冬氨酸β羟化酶抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human
应用： IF
稀释比例： IF 1:50-100.

抗体信息

靶标： ASPH
别名： AAH;BAH;CASQ2BP1;FDLAB;HAAH;JCTN;junctin
背景说明： This gene is thought to play an important role in calcium homeostasis. The gene is expressed from two promoters and undergoes extensive alternative splicing. The encoded set of proteins share varying amounts of overlap near their N-termini but have substantial variations in their C-terminal domains resulting in distinct functional properties. The longest isoforms (a and f) include a C-terminal Aspartyl/Asparaginyl beta-hydroxylase domain that hydroxylates aspartic acid or asparagine residues in the epidermal growth factor (EGF)-like domains of some proteins, including protein C, coagulation factors VII, IX, and X, and the complement factors C1R and C1S. Other isoforms differ primarily in the C-terminal sequence and lack the hydroxylase domain, and some have been localized to the endoplasmic and sarcoplasmic reticulum. Some of these isoforms are found in complexes with calsequestrin, triadin, and the ryanodine receptor, and have been shown to regulate calcium release from the sarcoplasmic reticulum. Some isoforms have been implicated in metastasis.
Swiss Prot： Q12797
Gene ID： 444
亚细胞定位： Endoplasmic reticulum membrane Sarcoplasmic reticulum membrane Single-pass type II membrane protein
免疫原： Recombinant protein of human ASPH
Public Immunogen Range： 81-270aa
理论分子量： 86kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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