Anti-ATP6V1B1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-ATP6V1B1 Polyclonal Antibody
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Human ; Rat
应用： IF ; WB
稀释比例： WB 1:500-2000.IF 1:50-200

抗体信息

靶标： ATP6V1B1
别名： ATP6B1;RTA1B;VATB;VMA2;VPP3
背景说明： This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain B subunit isoforms and is found in the kidney. Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness.
Swiss Prot： P15313
Gene ID： 525
亚细胞定位： Endomembrane system Peripheral membrane protein
免疫原： Recombinant protein of human ATP6V1B1
Public Immunogen Range： 1-280aa
理论分子量： 57kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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