Anti-PLOD2 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-PLOD2 Polyclonal Antibody
中文名称： 前胶原赖氨酸,2-氧戊二酸5-双加氧酶2抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Rat ; Mouse
应用： WB
稀释比例： WB 1:500-1000.

抗体信息

靶标： PLOD2
别名： LH2, Lysyl hydroxylase 2, PLOD2, TLH
背景说明： The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.
Swiss Prot： O00469
Gene ID： 5352
亚细胞定位： Lumenal side Peripheral membrane protein Rough endoplasmic reticulum membrane
免疫原： Recombinant protein of human PLOD2
Public Immunogen Range： 260-380aa
理论分子量： 85kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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