Anti-RFX5 Polyclonal Antibody,BR

英文名称:Anti-RFX5 Polyclonal Antibody
宿主:Rabbit
别名:RFX5
交叉反应:Human
应用:WB IF
稀释比例:WB 1:500-2000. IF 1:50-100.
蛋白分子量:65kDa
Gene ID:5993
保存:Store at -20°C. Avoid freeze / thaw cycles.
储存液:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法:Affinity purification
亚型:IgG
免疫原:Recombinant protein of human RFX5
性状:液体
亚细胞定位:Nucleus
Swiss Prot:P48382
背景资料:A lack of MHC-II expression results in a severe immunodeficiency syndrome called MHC-II deficiency, or the bare lymphocyte syndrome (BLS; MIM 209920). At least 4 complementation groups have been identified in B-cell lines established from patients with BLS. The molecular defects in complementation groups B, C, and D all lead to a deficiency in RFX, a nuclear protein complex that binds to the X box of MHC-II promoters. The lack of RFX binding activity in complementation group C results from mutations in the RFX5 gene encoding the 75-kD subunit of RFX (Steimle et al., 1995). RFX5 is the fifth member of the growing family of DNA-binding proteins sharing a novel and highly characteristic DNA-binding domain called the RFX motif. Multiple alternatively spliced transcript variants have been found but the full-length natures of only two have been determined.
Public Immunogen Range:Recombinant protein of human RFX5
克隆类型:Polyclonal Antibody
规格:50ul, 100ul, 注意：
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