Anti-UPF2 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-UPF2 Polyclonal Antibody
中文名称： hUPF2蛋白抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Human
应用： WB ; IHC ; IP
稀释比例： WB 1:500-2000. IHC 1:50-200. IP 0.5μg-4μg.

抗体信息

靶标： UPF2
别名： DKFZp434D222, hUpf2, KIAA1408, MGC138834, MGC138835, Nonsense mRNA reducing factor 2, Regulator of nonsense transcripts 2, RENT2, RENT2_HUMAN, Smg 3, Smg 3 homolog nonsense mediated mRNA decay factor, Up-frameshift suppressor 2 homolog, UPF2, UPF2 regulator of nonsense transcripts homolog, UROC1, Urocanate hydratase, Yeast Upf2p homolog
背景说明： This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene; both variants encode the same protein.
Swiss Prot： Q9HAU5
Gene ID： 26019
亚细胞定位： Cytoplasm perinuclear region
免疫原： Recombinant protein of human UPF2
Public Immunogen Range： 1153-1272aa
理论分子量： 148kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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