Anti-GLUD1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-GLUD1 Polyclonal Antibody
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Rat ; Human
应用： IP ; IF ; IHC ; WB
稀释比例： WB 1:500-1000. IHC 1:50-200. IF 1:50-200. IP 0.5μg-4μg.

抗体信息

靶标： GLUD1
别名： GDH,GDH1,GLUD,GLUD1,Glutamate dehydrogenase 1
背景说明： This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X.
Swiss Prot： P00367
Gene ID： 2746
亚细胞定位： Mitochondrion matrix
免疫原： Recombinant protein of human GLUD1
Public Immunogen Range： 54-242aa
理论分子量： 61kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
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注意事项 Considerations

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