Anti-SHC1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-SHC1 Polyclonal Antibody
中文名称： SHC(Src同源2结构域)转化蛋白1抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Mouse ; Human
应用： IF ; IHC ; WB
稀释比例： WB 1:500-1000.IHC 1:50-200.IF 1:50-200.

抗体信息

靶标： SHC1
别名： FLJ26504, p66, p66SHC, SH2 domain protein C1, SHC (Src homology 2 domain containing) transforming protein 1, SHC 1, SHC A, SHC adaptor protein 1, Shc, SHC transforming protein 1, SHC transforming protein, SHC-transforming protein 1, SHC-transforming protein 3, SHC-transforming protein A, SHC1, SHC1_HUMAN, SHCA, Src homology 2 domain-containing-transforming protein C1
背景说明： This gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2/SOS complex. p66Shc is not involved in Ras activation. Unlike the other two isoforms, p46Shc is targeted to the mitochondrial matrix. Several transcript variants encoding different isoforms have been found for this gene.
Swiss Prot： P29353
Gene ID： 6464
亚细胞定位： Cytoplasm Mitochondrion Mitochondrion matrix
免疫原： A synthetic peptide of human SHC1
Public Immunogen Range： 300-400aa
理论分子量： 63kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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