Anti-VRK1 Polyclonal Antibody,BR
Anti-VRK1 Polyclonal Antibody
(订货以英文名为准)
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宿主:Rabbit
别名:PCH1;PCH1A
交叉反应:Human Mouse Rat
应用:WB IHC
稀释比例:WB 1:500-2000. IHC 1:50-200.
蛋白分子量:45kDa
Gene ID:7443
保存:Store at -20°C. Avoid freeze / thaw cycles.
储存液:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法:Affinity purification
亚型:IgG
免疫原:Recombinant protein of human VRK1
性状:液体
亚细胞定位:Cytoplasm Nucleus
Swiss Prot:Q99986
背景资料:This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.
Public Immunogen Range:Recombinant protein of human VRK1
克隆类型:Polyclonal Antibody
规格:50ul, 100ul, 注意：
1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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