Anti-PDK3 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-PDK3 Polyclonal Antibody
中文名称： 丙酮酸脱氢酶激酶同工酶3抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Mouse ; Rat
应用： WB
稀释比例： WB 1:500-2000

抗体信息

靶标： PDK3
别名： [Pyruvate dehydrogenase [lipoamide] kinase isozyme 3 mitochondrial, [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, CMTX6, GS1-358P8.4, mitochondrial, PDK3, PDK3_HUMAN, Pyruvate dehydrogenase kinase isoenzyme 3, Pyruvate dehydrogenase kinase isoform 3, Pyruvate dehydrogenase kinase isozyme 3, Pyruvate dehydrogenase lipoamide kinase isozyme 3 mitochondrial
背景说明： The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle, and thus is one of the major enzymes responsible for the regulation of glucose metabolism. The enzymatic activity of PDH is regulated by a phosphorylation/dephosphorylation cycle, and phosphorylation results in inactivation of PDH. The protein encoded by this gene is one of the three pyruvate dehydrogenase kinases that inhibits the PDH complex by phosphorylation of the E1 alpha subunit. This gene is predominantly expressed in the heart and skeletal muscles. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Swiss Prot： Q15120
Gene ID： 5165
亚细胞定位： Mitochondrion matrix
免疫原： Recombinant protein of human PDK3
Public Immunogen Range： 137-406aa
理论分子量： 47kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。