Anti-ALOXE3 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-ALOXE3 Polyclonal Antibody
中文名称： 表皮型脂氧合酶3（鱼鳞病相关蛋白）抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Human ; Mouse
应用： WB
稀释比例： WB 1:500-2000

抗体信息

靶标： ALOXE3
别名： ALOXE3, Arachidonate lipoxygenase 3, e LOX 3, E LOX, e-LOX-3, eLOX3, Epidermal lipoxygenase, Epidermis-type lipoxygenase 3, Lipoxygenase 3, LOXE3_HUMAN
背景说明： This gene is a member of the lipoxygenase family, which are catabolized by arachidonic acid-derived compounds. The encoded enzyme is a hydroperoxide isomerase that synthesizes a unique type of epoxy alcohol (8R-hydroxy-11R,12R-epoxyeicosa-5Z,9E,14Z-trienoic acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). This epoxy alcohol can activate the the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha), which is implicated in epidermal differentiation. Loss of function of the enzyme encoded by this gene results in ichthyosis, implicating the function of this gene in the differentiation of human skin. This gene is part of a cluster of lipoxygenase genes on 17p13.1. Mutations in this gene result in nonbullous congenital ichthyosiform erythroderma (NCIE). Multiple transcript variants encoding different isoforms have been found for this gene.
Swiss Prot： Q9BYJ1
Gene ID： 59344
亚细胞定位： Cytoplasm
免疫原： Recombinant protein of human ALOXE3
Public Immunogen Range： 1-280aa
理论分子量： 81/95kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。