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- Anti-SMAD7 Polyclonal Antibody,BR
Anti-SMAD7 Polyclonal Antibody,BR
Anti-SMAD7 Polyclonal Antibody
(订货以英文名为准)猜你喜欢
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宿主:Rabbit
别名:MADH7;MADH8
交叉反应:Mouse Rat
应用:WB
稀释比例:WB 1:500-2000.
蛋白分子量:24/46kDa
Gene ID:4092
保存:Store at -20°C. Avoid freeze / thaw cycles.
储存液:Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法:Affinity purification
亚型:IgG
免疫原:Recombinant protein of human SMAD7
亚细胞定位:Cytoplasm Nucleus
Swiss Prot:O15105
背景资料:The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene.
克隆类型:Polyclonal Antibody
规格:50ul, 100ul, 注意:
1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
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